4'-Methoxy-α-pyrrolidinopropiophenone

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MOPPP SVG.svg
Systematic (IUPAC) name
(RS)-1-(4-methoxyphenyl)-2-(1-pyrrolidinyl)-1-propanone
Clinical data
Legal status
Routes of
administration
oral, insufflation, vaporization, IV
Identifiers
PubChem CID: 6430836
ChemSpider 4936174
UNII OI15TPX8QP YesY
Chemical data
Formula C14H19NO2
Molecular mass 233.305 g/mol
  • C2CCCN2C(C)C(=O)c(cc1)ccc1OC
  • InChI=1S/C14H19NO2/c1-11(15-9-3-4-10-15)14(16)12-5-7-13(17-2)8-6-12/h5-8,11H,3-4,9-10H2,1-2H3
  • Key:QJWOQBGBEFNYKB-UHFFFAOYSA-N

4'-Methoxy-α-pyrrolidinopropiophenone (MOPPP) is a stimulant drug, chemically similar to amphetamine ("speed") and MDMA ("ecstasy"). It is a designer drug and has the potential to produce a drug high.

Recreational usage

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MOPPP use is infrequent when compared to other amphetamines or stimulants used recreationally, such as meth, cocaine, or speed. It first arose as a designer drug in Germany in the late 1990s and early 2000s,[1][2][3] along with a number of other derivatives but never gained the international popularity[4][5] that other drugs in its family of pyrrolidinophenone derivatives had (such as α-PPP and MDPV).

While the recent trend of selling stimulants through false labeling (i.e., bath salts) has gained notoriety, using MDPV as its main ingredient, this has not been the case with MOPPP, despite its similar potential for abuse.[6]

Chemistry

MOPPP is structurally related to α-PPP in the same way that PMA is related to amphetamine: a methoxy group has been added to the 4-position on the phenyl ring.

Comparison of similar molecular structure
MOPPP

Metabolism

MOPPP appears to be metabolized within the liver chiefly by the enzyme CYP2D6.[2]

See also

References

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