Viqualine

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Viqualine
Viqualine.png
Systematic (IUPAC) name
4-[3-[(3R,4R)-3-Ethenylpiperidin-4-yl]propyl]-6-methoxyquinoline
Identifiers
CAS Number 72714-74-0
PubChem CID: 3050111
ChemSpider 2312222
UNII 1Y3A5E2L1J YesY
ChEMBL CHEMBL2104497
Chemical data
Formula C20H26N2O
Molecular mass 310.432 g/mol
  • COC1=CC2=C(C=CN=C2C=C1)CCC[C@@H]3CCNC[C@@H]3C=C
  • InChI=1S/C20H26N2O/c1-3-15-14-21-11-9-16(15)5-4-6-17-10-12-22-20-8-7-18(23-2)13-19(17)20/h3,7-8,10,12-13,15-16,21H,1,4-6,9,11,14H2,2H3/t15-,16+/m0/s1
  • Key:XFXANHWIBFMEOY-JKSUJKDBSA-N
  (verify)

Viqualine (INN) (developmental code name PK-5078) is an antidepressant and anxiolytic drug that was never marketed.[1][2][3] It acts as a potent and selective serotonin releasing agent and serotonin reuptake inhibitor.[3][4] In addition, viqualine displaces diazepam from the GABAA receptor and produces benzodiazepine-like effects, indicating that it is also a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.[3][5] The drug has mainly been researched as a potential treatment for alcoholism.[6][7]

See also

References

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