Safranal
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Names | |
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IUPAC names
2,6,6-trimethyl-1,3-
cyclohexadiene-1-carboxaldehyde |
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Identifiers | |
116-26-7 ![]() |
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ChEBI | CHEBI:53169 ![]() |
ChemSpider | 55000 ![]() |
Jmol 3D model | Interactive image |
PubChem | 61041 |
UNII | 4393FR07EA ![]() |
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Properties | |
C10H14O | |
Molar mass | 150.21 g/mol |
Density | 0.9734 g/cm3 |
Boiling point | 70 °C (158 °F; 343 K) at 1 mmHg |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Safranal is an organic compound isolated from saffron, the spice consisting of the stigmas of crocus flowers (Crocus sativus). It is the constituent primarily responsible for the aroma of saffron.
It is believed that safranal is a degradation product of the carotenoid zeaxanthin via the intermediacy of picrocrocin.
Pharmacology
Safranal is an effective anticonvulsant shown to act as an agonist at GABAA receptors.[1][2] Safranal also exhibits high antioxidant and free radical scavenging activity,[3][4] along with cytotoxicity towards cancer cells in vitro.[5] It has also been shown to have antidepressant properties.[6][7]
Natural sources
Natural sources of safranal include:[8]
- Microcystis (cyanobacterium)
- Aspalathus linearis (Rooibos)
- Camellia sinensis (Tea leaf)
- Crocus sativus (Saffron)
- Ficus carica (Fig leaf)
- Lycium chinense (Wolfberry)
- Cuminum cyminum (Cumin Seed)[9]
- Centaurea sibthorpii [10]
- Centaurea amanicola[10]
- Centaurea consanguinea[10]
- Erodium cicutarium (common stork's-bill or pinweed)[10]
- Calycopteris floribunda (Ukshi)[10]
- Sambucus nigra (elderberry)[10]
- Citrus limon (lemon)[10]
- Achillea distans [10]
References
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- Pages with reference errors
- Articles without KEGG source
- Pages using collapsible list with both background and text-align in titlestyle
- Chemical articles using a fixed chemical formula
- Aldehydes
- Antidepressants
- Saffron
- Monoterpenes
- GABAA receptor positive allosteric modulators
- Anticonvulsants
- Organic compound stubs
- Articles lacking reliable references from April 2010