CGS-20625

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CGS-20625
CGS-20625.svg
Systematic (IUPAC) name
5,6,7,8,9,10-hexahydro-2-(4-methoxyphenyl)-cyclohepta[b]pyrazolo[3,4-d]pyridin-3(2H)-one
Clinical data
Routes of
administration		 oral
Pharmacokinetic data
Bioavailability 41%
Identifiers
CAS Number 111205-55-1 YesY
ATC code none
PubChem CID: 163844
ChemSpider 143700 N
Chemical data
Formula C18H19N3O2
Molecular mass 309.36236 g/mol
  • COC1=CC=C(C=C1)N2C(=O)C3=CN=C4CCCCCC4=C3N2
  • InChI=1S/C18H19N3O2/c1-23-13-9-7-12(8-10-13)21-18(22)15-11-19-16-6-4-2-3-5-14(16)17(15)20-21/h7-11,20H,2-6H2,1H3 N
  • Key:UBLXQFIFWUEVGJ-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

CGS-20625 is an anxiolytic drug used in scientific research. It has similar effects to, and binds to the same target as benzodiazepine drugs,[1] but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[2][3]

CGS-20625 produces anxiolytic and anticonvulsant effects, but with no sedative effects even at high doses, and no significant muscle relaxant effects.[4] It is orally active in humans, but with relatively low bioavailability.[5]

References

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