Binedaline

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Binedaline
File:Binedaline.png
Systematic (IUPAC) name
N,N,N-trimethyl-N-(3-phenylindol-1-yl)ethane-1,2-diamine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration		 Oral
Identifiers
CAS Number 60662-16-0 N
ATC code none
PubChem CID: 42509
ChemSpider 38769 YesY
UNII 3AVG9P140R YesY
ChEMBL CHEMBL2104611 N
Chemical data
Formula C19H24ClN3
Molecular mass 329.86696 g/mol
  • c1cccc2c1c(cn2N(CCN(C)C)C)c3ccccc3
  • InChI=1S/C19H23N3/c1-20(2)13-14-21(3)22-15-18(16-9-5-4-6-10-16)17-11-7-8-12-19(17)22/h4-12,15H,13-14H2,1-3H3 YesY
  • Key:SXYFFMXPDDGOEK-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Binedaline (Ixprim), also called binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed.[1][2] It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 µM) transporters.[3] It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.[3]

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.


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